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Literature summary for 2.4.2.8 extracted from

  • Smithers, G.W.; O'Sullivan, W.J.
    Hypoxanthine phosphoribosyltransferase from human brain: purification and partial characterization (1984), Biochem. Med., 32, 106-121.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
24000
-
4 * 24000, SDS-PAGE Homo sapiens
100000
-
3 charge variant forms, native gradient gel electrophoresis Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
3 charge variant forms
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
guanine + 5-phospho-alpha-D-ribose 1-diphosphate
-
Homo sapiens GMP + diphosphate
-
?
hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate
-
Homo sapiens IMP + diphosphate
-
?

Subunits

Subunits Comment Organism
tetramer 4 * 24000, SDS-PAGE Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
additional information
-
3 charge variant forms with pIs of 5.7, 5.5 and 5.0 Homo sapiens