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Literature summary for 2.4.2.7 extracted from
- Structural complexes of human adenine phosphoribosyltransferase reveal novel features of the APRT catalytic mechanism (2008), J. Biomol. Struct. Dyn., 25, 589-597.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21(DE3) cells | Homo sapiens |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| hanging drop vapour diffusion method, with 15% (v/v) glycerol, 25.5% (w/v) PEG 4000, 0.17 M sodium acetate, and 0.085 M Tris-HCl, pH 8.5 | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P07741 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| hydroxyapathite column chromatography | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| adenine + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Homo sapiens | AMP + diphosphate | - |
? |  |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | x-ray crystallography | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| APRT | belongs to the type I phosphoribosyltransferase family | Homo sapiens |
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Release 2023.1 (January 2023)
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