Literature summary for 2.4.2.4 extracted from

Oberemm, A.; Meckert, C.; Brandenburger, L.; Herzig, A.; Lindner, Y.; Kalenberg, K.; Krause, E.; Ittrich, C.; Kopp-Schneider, A.; Stahlmann, R.; Richter-Reichhelm, H.; Gundert-Remy, U.
Differential signatures of protein expression in marmoset liver and thymus induced by single-dose TCDD treatment (2005), Toxicology, 206, 33-48.

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Application

Application	Comment	Organism
medicine	there is no tumour-selective depletion of thymidine and there does not appear to be any potential benefit of combining antibody-targeted thymidine phosphorylase with the thymidylate synthase inhibitor raltitrexed	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P19971	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HT-29 cell	-	Homo sapiens	-
LoVo cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
thymidine + phosphate	-	Homo sapiens	thymine + 2-deoxy-D-ribose 1-phosphate	-	?

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Release 2023.1 (January 2023)