Literature summary for 2.4.2.4 extracted from

Edwards, P.N.
A kinetic, modeling and mechanistic re-analysis of thymidine phosphorylase and some related enzymes (2006), J. Enzyme Inhib. Med. Chem., 21, 483-499.

Search for more literature for 2.4.2.4

Application

Application	Comment	Organism
medicine	important target enzyme for cancer chemotherapy	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P19971	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	molecular modeling based on an X-ray structure of human TP indicates that TP is likely to be mechanistically similar to all other natural members of the class in proceeding through a a oxacarbenium-like transition state or states	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)