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Literature summary for 2.4.2.31 extracted from

  • Belyy, A.; Tabakova, I.; Lang, A.E.; Jank, T.; Belyi, Y.; Aktories, K.
    Roles of Asp179 and Glu270 in ADP-ribosylation of actin by Clostridium perfringens iota toxin (2015), PLoS ONE, 10, e0145708.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.2.31

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NAD+ + [actin]-L-arginine177 Clostridium perfringens
-
 nicotinamide + [actin]-N-(ADP-D-ribosyl)-L-arginine177 + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Clostridium perfringens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information actin with substitution of Asp179 (but not Arg177 and less Glu270) is sensitive towards the toxic action of the enzyme Clostridium perfringens additional information
-
 ?
NAD+ + [actin]-L-arginine177
-
 Clostridium perfringens nicotinamide + [actin]-N-(ADP-D-ribosyl)-L-arginine177 + H+
-
 ?

Synonyms

Synonyms Comment Organism
binary toxin component Ia
-
 Clostridium perfringens
iota toxin
-
 Clostridium perfringens