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Literature summary for 2.4.2.30 extracted from

  • Infante, J.; Sanchez-Juan, P.; Mateo, I.; Rodriguez-Rodriguez, E.; Sanchez-Quintana, C.; Llorca, J.; Fontalba, A.; Terrazas, J.; Oterino, A.; Berciano, J.; Combarros, O.
    Poly (ADP-ribose) polymerase-1 (PARP-1) genetic variants are protective against Parkinsons disease (2007), J. Neurol. Sci., 256, 68-70.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
PARP-1, DNA and amino acid sequence determination and analysis of wild-type and mutant genes Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information analysis of polymorphisms of PARP-1 promoter sequence in Parkinson patients, variations in the regulatory region are probably involved in increased risk for the disease, overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme is involved in pathogenesis of Parkinson's disease, analysis of polymorphisms, overview ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
healthy people and Parkinson patients
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is involved in pathogenesis of Parkinson's disease, analysis of polymorphisms, overview Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
PARP-1
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Homo sapiens
poly (ADP-ribose) polymerase-1
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Homo sapiens