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Literature summary for 2.4.2.3 extracted from

  • Watanabe, S.; Hino, A.; Wada, K.; Eliason, J.F.; Uchida, T.
    Purification, cloning, and expression of murine uridine phosphorylase (1995), J. Biol. Chem., 270, 12191-12196.
    View publication on PubMed
Search for more literature for 2.4.2.3

Inhibitors

Inhibitors Comment Organism Structure
2,2'-Anhydro-5-ethyluridine competitive Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.064
-
 uridine
-
 Mus musculus
0.148
-
 thymidine
-
 Mus musculus
0.756
-
 5'-deoxy-5-fluorouridine
-
 Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
636
-
-
 Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5'-deoxy-5-fluorouridine + phosphate
-
 Mus musculus 5-fluorouracil + 5-deoxyribose-1-phosphate
-
 ?
thymidine + phosphate to a lesser extent compared to uridine Mus musculus thymine + 2-deoxy-alpha-D-ribose 1-phosphate
-
 ?
uridine + phosphate
-
 Mus musculus uracil + alpha-D-ribose 1-phosphate
-
 ?