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Literature summary for 2.4.2.3 extracted from

  • Naguib, F.N.M.; El Kouni, M.H.; Chu, S.H.; Cha, S.
    New analogues of benzylacyclouridines, specific and potent inhibitors of uridine phosphorylase from human and mouse livers (1987), Biochem. Pharmacol., 36, 2195-2201.
    View publication on PubMed
Search for more literature for 2.4.2.3

Inhibitors

Inhibitors Comment Organism Structure
5-(3'-Benzyloxybenzyl)-1-[(1'-aminomethyl-2'-hydroxyethoxy)methyl]uracil
-
 Homo sapiens
5-(3'-Benzyloxybenzyl)-1-[(1'-aminomethyl-2'-hydroxyethoxy)methyl]uracil
-
 Mus musculus
Benzylacyclouridines
-
 Homo sapiens
Benzylacyclouridines
-
 Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.076
-
 phosphate
-
 Mus musculus
0.143
-
 uridine
-
 Mus musculus
0.242
-
 uridine
-
 Homo sapiens
0.279
-
 phosphate
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Mus musculus
-
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
uridine + phosphate
-
 Mus musculus uracil + alpha-D-ribose 1-phosphate
-
 ?
uridine + phosphate
-
 Homo sapiens uracil + alpha-D-ribose 1-phosphate
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.000018
-
 5-(3'-Benzyloxybenzyl)-1-[(1'-aminomethyl-2'-hydroxyethoxy)methyl]uracil
-
 Mus musculus