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Literature summary for 2.4.2.26 extracted from

  • Stoolmiller, A.C.; Horwitz, A.L.; Dorfman, A.
    Biosynthesis of the chondroitin sulfate proteoglycan. Purification and properties of xylosyltransferase (1972), J. Biol. Chem., 247, 3525-3532.
    View publication on PubMed
Search for more literature for 2.4.2.26

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.025
-
 UDP-D-xylose
-
 Gallus gallus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Gallus gallus 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
110000 120000 gel filtration Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Gallus gallus involved in the biosynthesis of the linkage region of proteochondroitin sulfate ?
-
 ?
UDP-alpha-D-xylose + [protein]-L-serine Gallus gallus
-
 UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Gallus gallus

Source Tissue

Source Tissue Comment Organism Textmining
brain 8% activity compared to epiphyseal cartilage Gallus gallus
-
cartilage embryonic Gallus gallus
-
cartilage epiphyseal Gallus gallus
-
epiphysis highest activity Gallus gallus
-
epiphysis cartilage Gallus gallus
-
additional information no activity in liver and intestine with an exogenous receptor Gallus gallus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Gallus gallus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information involved in the biosynthesis of the linkage region of proteochondroitin sulfate Gallus gallus ?
-
 ?
UDP-alpha-D-xylose + [protein]-L-serine
-
 Gallus gallus UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
UDP-alpha-D-xylose + [protein]-L-serine exogenous protein acceptor obtained by Smith degradation of bovine chondroitin sulfate-protein complex Gallus gallus UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
UDP-alpha-D-xylose + [protein]-L-serine transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate Gallus gallus UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Gallus gallus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5 7
-
 Gallus gallus

pH Range

pH Minimum pH Maximum Comment Organism
5.7 7.5 half-maximal activity at pH 5.7 and pH 7.5 Gallus gallus