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Literature summary for 2.4.2.2 extracted from

  • Pugmire, M.J.; Ealick, S.E.
    The crystal structure of pyrimidine nucleoside phosphorylase in a closed conformation (1998), Structure, 6, 1467-1479.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
crystal structure of the enzyme with the substrate analog, pseudouridine, in its active site is solved to 2.1 A Geobacillus stearothermophilus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Geobacillus stearothermophilus reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway ?
-
?

Organism

Organism UniProt Comment Textmining
Geobacillus stearothermophilus
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway Geobacillus stearothermophilus ?
-
?
thymidine + phosphate
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Geobacillus stearothermophilus thymine + 2-deoxy-D-ribose 1-phosphate
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?
uridine + phosphate
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Geobacillus stearothermophilus uracil + alpha-D-ribose 1-phosphate
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?