Crystallization (Comment) | Organism |
---|---|
- |
Sus scrofa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | 2 mM, 25% inhibition | Sus scrofa | |
ATP | 2 mM, 82% inhibition | Sus scrofa | |
Cu2+ | 1 mM, 87% inhibition | Sus scrofa | |
Fe2+ | 1 mM, 93% inhibition | Sus scrofa | |
Monoiodoacetic acid | 5 mM, 50% inhibition | Sus scrofa | |
PCMB | 0.05 mM, complete inhibition | Sus scrofa | |
Phthalic acid | competitive to quinolinate | Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.12 | - |
quinolinate | - |
Sus scrofa | |
0.18 | - |
5-phospho-alpha-D-ribose 1-diphosphate | - |
Sus scrofa |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | optimal Mg2+ concentration: 1 mM | Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
33500 | - |
x * 33500, SDS-PAGE | Sus scrofa |
202000 | - |
equilibrium sedimentation | Sus scrofa |
210000 | - |
gel filtration | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
beta-nicotinate D-ribonucleotide + diphosphate + CO2 = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate | formation of a ternary complex consisting the enzyme, pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate | Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.05169 | - |
- |
Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Sus scrofa | nicotinate D-ribonucleotide + diphosphate + CO2 | i.e. beta-niacin mononucleotide | ? |
Subunits | Comment | Organism |
---|---|---|
? | x * 33500, SDS-PAGE | Sus scrofa |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.1 | - |
- |
Sus scrofa |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
5.5 | 10 | - |
Sus scrofa |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.17 | - |
Phthalic acid | - |
Sus scrofa |