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Literature summary for 2.4.2.18 extracted from

  • Marcus, S.L.; Balbinder, E.
    Purification of anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase from Salmonella typhimurium using affinity chromatography: resolution of monomeric and dimeric forms (1972), Biochem. Biophys. Res. Commun., 47, 438-444.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
70000
-
and 150000, disc gel electrophoresis Salmonella enterica subsp. enterica serovar Typhimurium
150000
-
and 70000, disc gel electrophoresis Salmonella enterica subsp. enterica serovar Typhimurium

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate Salmonella enterica subsp. enterica serovar Typhimurium enzyme of tryptophan biosynthesis N-(5-phospho-D-ribosyl)-anthranilate + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Purification (Commentary)

Purification (Comment) Organism
unaggregated form Salmonella enterica subsp. enterica serovar Typhimurium

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.54
-
-
Salmonella enterica subsp. enterica serovar Typhimurium
1540
-
-
Salmonella enterica subsp. enterica serovar Typhimurium

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate
-
Salmonella enterica subsp. enterica serovar Typhimurium N-(5-phospho-D-ribosyl)-anthranilate + diphosphate
-
?
anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate enzyme of tryptophan biosynthesis Salmonella enterica subsp. enterica serovar Typhimurium N-(5-phospho-D-ribosyl)-anthranilate + diphosphate
-
?

Subunits

Subunits Comment Organism
? enzyme exists in both monomeric and dimeric forms, SDS-PAGE Salmonella enterica subsp. enterica serovar Typhimurium
More in some organisms, this enzyme is part of a multifunctional protein together with one or more other components of the system for biosynthesis of tryptophan: EC 4.1.1.48, EC 4.1.3.27, EC 4.2.1.20, EC 5.3.1.24 Salmonella enterica subsp. enterica serovar Typhimurium
More anthranilate synthase-phosphoribosylanthranilate transferase complex exists in Citrobacter species in all other bacteria examined phosphoribosylanthranilate transferase and anthranilate synthase are separate enzyme molecules Salmonella enterica subsp. enterica serovar Typhimurium

Synonyms

Synonyms Comment Organism
More in some organisms, this enzyme is part of a multifunctional protein together with one or more other components of the system for biosynthesis of tryptophan (EC 4.1.1.48, EC 4.1.3.27, EC 4.2.1.20, EC 5.3.1.24) Salmonella enterica subsp. enterica serovar Typhimurium