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Literature summary for 2.4.2.14 extracted from

  • Jimenez, A.; Santos, M.A.; Pompejus, M.; Revuelta, J.L.
    Metabolic engineering of the purine pathway for riboflavin production in Ashbya gossypii (2005), Appl. Environ. Microbiol., 71, 5743-5751.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
-
Eremothecium gossypii

Protein Variants

Protein Variants Comment Organism
A417W moderate resistance to inhibition by ATP or GPT Eremothecium gossypii
D310V almost resistant to inhibition by ATP or GTP, low concentrations of ATP plus GTP activate Eremothecium gossypii
K333Q almost resistant to inhibition by ATP or GTP, low concentrations of ATP plus GTP activate Eremothecium gossypii
additional information enzyme deletion mutant, auxotrophic for adenine, produces lower levels of riboflavin than wild-type Eremothecium gossypii

Inhibitors

Inhibitors Comment Organism Structure
ATP 10 mM, 10% residual activity Eremothecium gossypii
GTP 10 mM, 10% residual activity Eremothecium gossypii

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
56700
-
x * 56700, calculated Eremothecium gossypii

Organism

Organism UniProt Comment Textmining
Eremothecium gossypii
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3
-
wild-type, pH 8.0, 37°C Eremothecium gossypii

Subunits

Subunits Comment Organism
? x * 56700, calculated Eremothecium gossypii

Synonyms

Synonyms Comment Organism
ADE4
-
Eremothecium gossypii