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Literature summary for 2.4.2.12 extracted from
- Salidroside protects PC12 cells from Abeta1-40-induced cytotoxicity by regulating the nicotinamide phosphoribosyltransferase signaling pathway (2017), Mol. Med. Rep., 16, 2700-2706 .
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| nicotinamide D-ribonucleotide + diphosphate | Rattus norvegicus | - |
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | Q80Z29 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| PC-12 cell | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| nicotinamide D-ribonucleotide + diphosphate | - |
Rattus norvegicus | nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Nampt | - |
Rattus norvegicus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Rattus norvegicus | the expression level of the enzyme decreases as a result of Abeta1-40x1einduced neuronal toxicity | down |
| Rattus norvegicus | administration of 0.1 mM salidroside alleviates Abetax1einduced cell damage and increases the expression level of the enzyme | up |
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Release 2023.1 (January 2023)
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