Inhibitors | Comment | Organism | Structure |
---|---|---|---|
FK866 | - |
Homo sapiens | |
FK866 | - |
Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate | Mus musculus | - |
nicotinamide D-ribonucleotide + diphosphate | - |
? | |
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate | Homo sapiens | - |
nicotinamide D-ribonucleotide + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P43490 | - |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lymphocyte | - |
Mus musculus | - |
lymphocyte | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Mus musculus | nicotinamide D-ribonucleotide + diphosphate | - |
? | |
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Homo sapiens | nicotinamide D-ribonucleotide + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Nampt | - |
Mus musculus |
Nampt | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme inhibition induces NAD depletion in various mouse organs but selectively causes dramatic atrophy of the spleen red pulp | Mus musculus |
physiological function | enzyme activity is essential for survival of resting lymphocytes | Mus musculus |
physiological function | enzyme activity is essential for survival of resting lymphocytes | Homo sapiens |