Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
H247A | active site residue, no detectable activity | Homo sapiens |
H247E | active site residue, low activity | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
FK-866 | i.e. (2E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-phenylprop-2-enamide | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
55520 | - |
2 * 55520, theoretic value | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P43490 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | autophosphorylation can increase the activity | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
heart | - |
Homo sapiens | - |
kidney | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
lung | - |
Homo sapiens | - |
lymphocyte | - |
Homo sapiens | - |
pancreas | - |
Homo sapiens | - |
placenta | - |
Homo sapiens | - |
skeletal muscle | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
nicotinamide + 5-phosphoribosyl 1-diphosphate | - |
Homo sapiens | nicotinamide mononucleotide + diphosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
homodimer | 2 * 55520, theoretic value | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
nicotinamide phosphoribosyltransferase | - |
Homo sapiens |
pre-B-cell colony enhancing factor | - |
Homo sapiens |
Visfatin | - |
Homo sapiens |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Homo sapiens | theoretic value | - |
6.69 |
General Information | Comment | Organism |
---|---|---|
malfunction | implicated in the pathogenesis of a number of human diseases or conditions such as acute lung injury, aging, atherosclerosis, cancer, diabetes, rheumatoid arthritis and sepsis | Homo sapiens |
physiological function | growth factor, cytokine and nicotinamide phosphoribosyltransferase | Homo sapiens |