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Literature summary for 2.4.2.10 extracted from
- Overexpression of orotate phosphoribosyl transferase in hormone-refractory prostate cancer (2009), Oncol. Rep., 21, 33-37.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| prostate gland | normal tissue, hormone-sensitive prostate cancer (HSPC) or hormonerefractory prostate cancer (HRPC) tissue | Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| OPRT | - |
Homo sapiens |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | low expression in normal prostate gland tissue | down |
| Homo sapiens | strong expression of OPRT in prostate cancer cells, significant correlation between OPRT mRNA expression levels and the tumor pathological grade. The OPRT/dihydropyrimidine dehydrogenase expression ratio in the HRPC group is significantly higher than that in the low grade HSPC group | up |
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Release 2023.1 (January 2023)
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