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Literature summary for 2.4.2.10 extracted from

  • Nio, Y.; Toga, T.; Maruyama, R.; Fukushima, M.
    Expression of orotate phosphoribosyl transferase in human pancreatic cancer: implication for the efficacy of uracil and tegafur-based adjuvant chemotherapy (2007), Oncol. Rep., 18, 59-64.
    View publication on PubMed

Application

Application Comment Organism
medicine the expression of OPRT may be useful to predict the response to adjuvant chemotherapy with 5-fluorouracil in human pancreatic cancer Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreatic cancer cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-fluorouracil + 5-phospho-alpha-D-ribose 1-diphosphate
-
Homo sapiens 5-fluorouridine 5'-phosphate + diphosphate
-
?

Synonyms

Synonyms Comment Organism
OPRT
-
Homo sapiens