Literature summary for 2.4.2.1 extracted from

Wielgus-Kutrowska, B.; Bzowska, A.
Kinetic properties of Cellulomonas sp. purine nucleoside phosphorylase with typical and non-typical substrates: implications for the reaction mechanism (2005), Nucleosides Nucleotides Nucleic Acids, 24, 471-476.

Search for more literature for 2.4.2.1

Inhibitors

Inhibitors	Comment	Organism	Structure
alpha-D-ribose 1-phosphate	mixed inhibition	Cellulomonas sp.
guanine	competitive versus phosphate and inosine	Cellulomonas sp.
guanosine	uncompetitive inhibition of alpha-D-ribose 1-phosphate	Cellulomonas sp.
phosphate	uncompetitive versus guanine	Cellulomonas sp.

Organism

Organism	UniProt	Comment	Textmining
Cellulomonas sp.	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
7-methylguanosine + phosphate	-	Cellulomonas sp.	7-methylguanine + alpha-D-ribose 1-phosphate	-	r
guanine + alpha-D-ribose 1-phosphate	-	Cellulomonas sp.	guanosine + phosphate	-	?
inosine + phosphate	-	Cellulomonas sp.	hypoxanthine + alpha-D-ribose 1-phosphate	-	r

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.0025	-	guanine	versus phosphate	Cellulomonas sp.
0.0036	-	guanine	versus inosine	Cellulomonas sp.
0.8	-	guanosine	versus alpha-D-ribose 1-phosphate	Cellulomonas sp.
4.7	-	phosphate	versus guanine	Cellulomonas sp.

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Release 2023.1 (January 2023)