Any feedback?
Literature summary for 2.4.1.92 extracted from
- beta1,4-N-acetylgalactosaminyltransferase-GM2/GD2 synthase: a key enzyme to control the synthesis of brain-enriched complex gangliosides (2002), Biochim. Biophys. Acta, 1573, 356-362.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | - |
Homo sapiens |
| additional information | overexpression of gene leads to shift of ganglioside components from b-series to a-series | Mus musculus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| Golgi apparatus | - |
Homo sapiens | 5794 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q00973 | - |
- |
| Mus musculus | Q09200 | - |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | 3 N-glycosylation sites at 79,179, 274 | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | overview on substrate specificity | Homo sapiens | ? | - |
? |  |
| UDP-N-acetyl-D-galactosamine + (N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide | i.e. GM3(N-acetylneuraminic acid), best substrate | Homo sapiens | UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide | - |
? | |
| UDP-N-acetyl-D-galactosamine + GD3-ganglioside | - |
Homo sapiens | UDP + GD2-ganglioside | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
