Application | Comment | Organism |
---|---|---|
medicine | the Bacillus thuringiensis phosphatidylinositol-specific phospholipase C and the alpha(1,3)GT genes are engineered to be delivered to cells in two separate retroviral vectors. Activity of phosphatidylinositol-specific phospholipase C, secreted from transduced A549 human lung tumor cells shows a synergistic increase in alphagal mediated complement killing in an in vitro assay. When applied to in vivo therapy of solid tumors, this approach may enhance anti-tumor immune responses | Mus musculus |
Cloned (Comment) | Organism |
---|---|
murine alpha(1,3)GT gene is cloned into the Moloney murine leukemia retroviral vector, pLNCX, giving rise to pLNCKG expression in A549 human lung tumor cells | Mus musculus |
Organism | UniProt | Comment | Textmining |
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Mus musculus | - |
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- |