Cloned (Comment) | Organism |
---|---|
capillary endothelial cell clone overexpressing the gene encoding DPMS | synthetic construct |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
synthetic construct | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
DPMS | - |
synthetic construct |
mannosylphosphodolichol synthase | - |
synthetic construct |
Organism | Comment | Expression |
---|---|---|
synthetic construct | the DPMS-overexpressing clone has a high level of DPMS mRNA, expresses nearly 4times more DPMS protein than the clone transfected with pEGFP-N1 vector only and has 108% higher DPMS activity than the vector control | up |
General Information | Comment | Organism |
---|---|---|
physiological function | high level of expression of (GlcNAc-beta-(1,4)-GlcNAc) 1-4-beta-GlcNAc-NeuAc glycans on the external surface of the capillary endothelial cells overexpressing DPMS. Increased cellular proliferation and accelerated healing of the wound induced by mechanical stress of the DPMS-overexpressing clone unequivocally supports a role of DPMS in angiogenesis | synthetic construct |