Literature summary for 2.4.1.80 extracted from

Paul, P.; Lutz, T.M.; Osborn, C.; Kyosseva, S.; Elbein, A.D.; Towbin, H.; Radominska, A.; Drake, R.R.
Synthesis and characterization of a new class of inhibitors of membrane-associated UDP-glycosyltransferases (1993), J. Biol. Chem., 268, 12933-12938.

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Inhibitors

Inhibitors	Comment	Organism	Structure
PP55B	i.e. isopropylidene derivative of 5'-O-[[(2-decanoylamino-3-phenylpropylloxycarbonyl)amino]sulfonyl]uridine, 21% inhibition at 0.2 mM	Mus musculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
microsome	-	Mus musculus	-	-

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Mus musculus	-
liver	-	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
UDP-glucose + N-acylsphingosine	i.e. ceramide	Mus musculus	UDP + D-glucosyl-N-acylsphingosine	i.e. glucosylceramide	?

Synonyms

Synonyms	Comment	Organism
GlcT	-	Mus musculus

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Release 2023.1 (January 2023)