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Literature summary for 2.4.1.68 extracted from

  • Shao, M.C.; Sokolik, C.W.; Wold, F.
    Specificity studies of the GDP-[L]-fucose:2-acetamido-2-deoxy-beta-[D]-glucoside (Fuc-Asn-linked GlcNAc) 6-alpha-[L]-fucosyltransferase from rat-liver Golgi membranes (1994), Carbohydr. Res., 251, 163-173.
    View publication on PubMed
Search for more literature for 2.4.1.68

Inhibitors

Inhibitors Comment Organism Structure
streptavidin inhibition due to stereochemical blockage of the fucosylation site Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi membrane
-
 Rattus norvegicus 139
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP-beta-fucose + (N-acetylglucosaminyl)2-Man3-GlcNAc2-(6-biotinamidohexanoyl)asparagine
-
 Rattus norvegicus GDP + L-fucose alpha-1,6 bound to the asparagine-linked N-acetylglucosamine of (N-acetylglucosaminyl)2-Man3-GlcNAc2-(6-biotinamidohexanoyl)asparagine
-
 ?
GDP-beta-fucose + Gal-N-acetylglucosaminyl-Man5-GlcNAc2-(6-biotinamidohexanoyl)asparagine low activity Rattus norvegicus GDP + L-fucose alpha-1,6 bound to the asparagine-linked N-acetylglucosamine of Gal-N-acetylglucosaminyl-Man5-GlcNAc2-(6-biotinamidohexanoyl)asparagine
-
 ?
GDP-beta-fucose + Gal2-(N-acetylglucosaminyl)2-Man3-GlcNAc2-(6-biotinamidohexanoyl)asparagine low activity Rattus norvegicus GDP + L-fucose alpha-1,6 bound to the asparagine-linked N-acetylglucosamine of Gal2-(N-acetylglucosaminyl)2-Man3-GlcNAc2-(6-biotinamidohexanoyl)asparagine
-
 ?
GDP-beta-fucose + N-acetylglucosaminyl-Man3-GlcNAc2-(6-biotinamidohexanoyl)asparagine best substrate Rattus norvegicus GDP + L-fucose alpha-1,6 bound to the asparagine-linked N-acetylglucosamine of N-acetylglucosaminyl-Man3-GlcNAc2-(6-biotinamidohexanoyl)asparagine
-
 ?
GDP-beta-fucose + N-acetylglucosaminyl-Man5-GlcNAc2-(6-biotinamidohexanoyl)asparagine
-
 Rattus norvegicus GDP + L-fucose alpha-1,6 bound to the asparagine-linked N-acetylglucosamine of N-acetylglucosaminyl-Man5-GlcNAc2-(6-biotinamidohexanoyl)asparagine
-
 ?
additional information substrate specificity Rattus norvegicus ?
-
 ?
additional information no activity with Man5-GlcNAc2-(6-biotinamidohexanoyl)asparagine, Sia-Gal2-GlcNAc2-Man3-GlcNAc2-(6-biotinamidohexanoyl)asparagine and Sia2-Gal2-GlcNAc2-Man3-GlcNAc2-(6-biotinamidohexanoyl)asparagine Rattus norvegicus ?
-
 ?

Synonyms

Synonyms Comment Organism
alpha1,6-fucosyltransferase
-
 Rattus norvegicus
GDP-L-fucose:2-acetamido-2-deoxy-beta-D-glucoside 6-alpha-L-fucosyltransferase Fuc-Asn-linked N-acetylglucosamine Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.7
-
 assay at Rattus norvegicus