Literature summary for 2.4.1.62 extracted from

Amado, M.; Almeida, R.; Carneiro, F.; Levery, S.B.; Holmes, E.H.; Nomoto, M.; Hollingsworth, M.A.; Hassan, H.; Schwientek, T.; Nielsen, P.A.; Bennett, E.P.; Clausen, H.
A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta-acetyl-galactosamine beta-1,3-galactosyltransferase family (1998), J. Biol. Chem., 273, 12770-12778.

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Cloned(Commentary)

Cloned (Comment)	Organism
amino acid sequence determination, expression in Sf9 insect cells via baculovirus transfection	Homo sapiens
cloning and DNA sequencing, amino acid sequence determination, expression in Sf9 insect cells via baculovirus transfection	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
additional information	-	amino acid sequence alignment	Homo sapiens
additional information	-	amino acid sequence alignment	Drosophila melanogaster

Organism

Organism	UniProt	Comment	Textmining
Drosophila melanogaster	Q24157	-	-
Homo sapiens	O43825	isoform beta3Gal-T2	-
Homo sapiens	O75752	isoform beta3Gal-T4	-
Homo sapiens	O96024	isoform beta3Gal-T1	-
Homo sapiens	O96024	isoform beta3Gal-T3	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
glycoprotein	glycosylation sites, overview	Homo sapiens
glycoprotein	glycosylation sites, overview	Drosophila melanogaster

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Homo sapiens	-
heart	-	Homo sapiens	-
additional information	widely distributed	Homo sapiens	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	-	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine	donor and acceptor specificity, overview	Homo sapiens	UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine	-	?

Synonyms

Synonyms	Comment	Organism
beta3Gal-T	-	Homo sapiens
UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase	-	Homo sapiens

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Release 2023.1 (January 2023)