Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | nutritional inadequacy during the active growth phase of the brain causes significantly diminished enzyme activity | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | last step in biosynthesis of cerebrosides | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Wistar rats | - |
Rattus norvegicus | - |
7, 14 and 21 days old | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | cerebrum, cerebellum and brain stem of 14 and 21 days old rats, whole brain of 7 days old rats | Rattus norvegicus | - |
brain stem | cerebrum, cerebellum and brain stem of 14 and 21 days old rats | Rattus norvegicus | - |
cerebellum | cerebrum, cerebellum and brain stem of 14 and 21 days old rats | Rattus norvegicus | - |
cerebrum | cerebrum, cerebellum and brain stem of 14 and 21 days old rats | Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
more, specific activity is maximal at about 21 days and then gradually declines | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | last step in biosynthesis of cerebrosides | Rattus norvegicus | ? | - |
? | |
UDPgalactose + 2-(2-hydroxyacyl)sphingosine | i.e. 2-hydroxy fatty acid ceramide | Rattus norvegicus | 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine + UDP | cerebroside | ? |