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Literature summary for 2.4.1.41 extracted from

  • Toba, S.; Tenno, M.; Konishi, M.; Mikami, T.; Itoh, N.; Kurosaka, A.
    Brain-specific expression of a novel human UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T9) (2000), Biochim. Biophys. Acta, 1493, 264-268.
    View publication on PubMed
Search for more literature for 2.4.1.41

Cloned(Commentary)

Cloned (Comment) Organism
GalNAc-T9 is cloned and characterized encoding a 603 amino acid protein, nucleotide and amino acid sequence Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane GalNAc-T9: type II membrane protein with a 20-amino acid transmembrane domain, a 7-amino acid cytoplasmic domain and a 91-amino acid stem region Homo sapiens 16020
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-N-acetyl-D-galactosamine + polypeptide Homo sapiens GalNAc-T9 catalyzes O-glycosylation in brain UDP + N-acetyl-D-galactosaminyl-polypeptide
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 ?
UDP-N-acetyl-D-galactosamine + polypeptide Homo sapiens primary step in the production of mucin-type O-linked oligosaccharide groups in glycoproteins UDP + N-acetyl-D-galactosaminyl-polypeptide
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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 GalNAc-T9
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Source Tissue

Source Tissue Comment Organism Textmining
brain brain-specific expression of GalNAc-T9, mRNA is most abundant in cerebellum, lower levels in cerebral cortex, frontal lobe, temporal lobe and putamen Homo sapiens
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sublingual gland GalNAc-T5 is most abundant in Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information multiple enzyme isoforms Homo sapiens ?
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 ?
additional information GalNAc-T9 contains a 485-amino acid putative catalytic region, GalNAc-T1, -T2, -T4 and -T8 belongs to the housekeeping enzymes with ubiquitous expression, GalNAc-T3, -T5, -T6, -T7 and -T9 belongs to the tissue-specific enzymes Homo sapiens ?
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 ?
additional information amino acid sequences of seven GalNAc-transferases Homo sapiens ?
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 ?
UDP-N-acetyl-D-galactosamine + polypeptide
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 Homo sapiens UDP + N-acetyl-D-galactosaminyl-polypeptide
-
 ?
UDP-N-acetyl-D-galactosamine + polypeptide GalNAc-T9 catalyzes O-glycosylation in brain Homo sapiens UDP + N-acetyl-D-galactosaminyl-polypeptide
-
 ?
UDP-N-acetyl-D-galactosamine + polypeptide primary step in the production of mucin-type O-linked oligosaccharide groups in glycoproteins Homo sapiens UDP + N-acetyl-D-galactosaminyl-polypeptide
-
 ?