Protein Variants | Comment | Organism |
---|---|---|
Y285I | site-directed mutagenesis, the mutation converts the betaGALT1 enzyme into an equally efficient beta4GalNAc-T1, EC 2.4.1.90 | Homo sapiens |
Y285L | site-directed mutagenesis, the mutation converts the betaGALT1enzyme into an equally efficient beta4GalNAc-T1, EC 2.4.1.90 | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | required | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide | Homo sapiens | - |
UDP + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminylglycopeptide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide | - |
Homo sapiens | UDP + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminylglycopeptide | - |
? | |
UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide | residue Y285 alone is responsible for determination of enzyme substrate specificity, overview, active site structure, overview | Homo sapiens | UDP + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminylglycopeptide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
beta1,4-galactosyltransferase-1 | - |
Homo sapiens |
betaGALT1 | - |
Homo sapiens |
GalT1 | - |
Homo sapiens |
More | cf. EC 2.4.1.90 | Homo sapiens |