Activating Compound | Comment | Organism | Structure |
---|---|---|---|
AKnT protein | the optimal ratio of AknS to AknT is 1:3 | Streptomyces galilaeus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.005 | - |
aklavinone | in the presence of activator protein AknT, at pH 7.5 and 25°C | Streptomyces galilaeus | |
0.013 | - |
aklavinone | in the absence of activator protein AknT, at pH 7.5 and 25°C | Streptomyces galilaeus | |
0.28 | - |
dTDP-beta-L-rhodosamine | in the presence of activator protein AknT, at pH 7.5 and 25°C | Streptomyces galilaeus | |
0.349 | - |
dTDP-beta-L-rhodosamine | in the absence of activator protein AknT, at pH 7.5 and 25°C | Streptomyces galilaeus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dTDP-beta-L-rhodosamine + aklavinone | Streptomyces galilaeus | - |
dTDP + rhodosaminyl-aklavinone | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces galilaeus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dTDP-beta-L-rhodosamine + aklavinone | - |
Streptomyces galilaeus | dTDP + aclacinomycin T | - |
? | |
dTDP-beta-L-rhodosamine + aklavinone | - |
Streptomyces galilaeus | dTDP + rhodosaminyl-aklavinone | - |
? | |
dTDP-L-2-deoxyfucose + aklavinone | - |
Streptomyces galilaeus | dTDP + 4-O-(2-deoxy-alpha-L-fucosyl)aklavinone | - |
? | |
dTDP-L-daunosamine + aklavinone | - |
Streptomyces galilaeus | dTDP + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AknS/AknT | - |
Streptomyces galilaeus |
Gtf | - |
Streptomyces galilaeus |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0083 | - |
dTDP-beta-L-rhodosamine | in the absence of activator protein AknT, at pH 7.5 and 25°C | Streptomyces galilaeus | |
0.16 | - |
dTDP-beta-L-rhodosamine | at pH 7.5 and 25°C | Streptomyces galilaeus |