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Literature summary for 2.4.1.287 extracted from

  • Mikusova, K.; Belanova, M.; Kordulakova, J.; Honda, K.; McNeil, M.; Mahapatra, S.; Crick, D.; Brennan, P.
    Identification of a novel galactosyl transferase involved in biosynthesis of the mycobacterial cell wall (2006), J. Bacteriol., 188, 6592-6598.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.1.287

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Mycobacterium smegmatis mc2155 cells Mycobacterium tuberculosis

Localization

Localization Comment Organism GeneOntology No. Textmining
cell wall
-
 Mycobacterium tuberculosis 5618
-
membrane
-
 Mycobacterium tuberculosis 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
33863
-
 x * 33863, calculated from amino acid sequence Mycobacterium tuberculosis

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis
-
-
-
Mycobacterium tuberculosis H37Rv
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Talon resin column chromatography Mycobacterium tuberculosis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the bifunctional enzyme is responsible for the initial synthesis of C50-P-P-GlcNAc-Rha-Galf, followed by immediate conversion to C50-P-P-GlcNAc-Rha-Galf-Galf Mycobacterium tuberculosis ?
-
 ?
additional information the bifunctional enzyme is responsible for the initial synthesis of C50-P-P-GlcNAc-Rha-Galf, followed by immediate conversion to C50-P-P-GlcNAc-Rha-Galf-Galf Mycobacterium tuberculosis H37Rv ?
-
 ?
UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
 Mycobacterium tuberculosis UDP + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
 ?
UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
 Mycobacterium tuberculosis H37Rv UDP + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
 ?

Subunits

Subunits Comment Organism
? x * 33863, calculated from amino acid sequence Mycobacterium tuberculosis

Synonyms

Synonyms Comment Organism
galactosyl transferase
-
 Mycobacterium tuberculosis
GalTr
-
 Mycobacterium tuberculosis
Rv3782
-
 Mycobacterium tuberculosis

General Information

General Information Comment Organism
physiological function the enzyme is involved in biosynthesis of the mycobacterial cell wall Mycobacterium tuberculosis