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Literature summary for 2.4.1.258 extracted from

  • Verostek, M.F.; Atkinson, P.H.; Trimble, R.B.
    Structure of Saccharomyces cerevisiae alg3,sec18 mutant oligosaccharides (1991), J. Biol. Chem., 266, 5547-5551.
    View publication on PubMed
Search for more literature for 2.4.1.258

Protein Variants

Protein Variants Comment Organism
additional information alg3 mutant Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Saccharomyces cerevisiae involved in oligosaccharide-lipid synthesis ?
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 ?
additional information Saccharomyces cerevisiae A involved in oligosaccharide-lipid synthesis ?
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 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P38179
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Saccharomyces cerevisiae P38179 A
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Saccharomyces cerevisiae A P38179 A
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP-alpha-D-mannose + Manalpha(1-2)Manalpha(1-2)Manalpha(1-3)(Manalpha(1-6))Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-PP-dolichol alg3 Man5GlcNAc2 precursor Saccharomyces cerevisiae GDP + Manalpha(1-2)Manalpha(1-2)Manalpha(1-3)(Manalpha(1-3)Manalpha(1-6))Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-PP-dolichol
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 ?
GDP-alpha-D-mannose + Manalpha(1-2)Manalpha(1-2)Manalpha(1-3)(Manalpha(1-6))Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-PP-dolichol alg3 Man5GlcNAc2 precursor Saccharomyces cerevisiae A GDP + Manalpha(1-2)Manalpha(1-2)Manalpha(1-3)(Manalpha(1-3)Manalpha(1-6))Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-PP-dolichol
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 ?
additional information involved in oligosaccharide-lipid synthesis Saccharomyces cerevisiae ?
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 ?
additional information involved in oligosaccharide-lipid synthesis Saccharomyces cerevisiae A ?
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 ?

General Information

General Information Comment Organism
malfunction alg3 yeast accumulates Man5GlcNAc2-P-P-dolichol due to a defective alphal,3-mannosyltransferase required for the next step in oligosaccharide-lipid elongation Saccharomyces cerevisiae