Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.1.255 extracted from

  • Kim, E.J.; Abramowitz, L.K.; Bond, M.R.; Love, D.C.; Kang, D.W.; Leucke, H.F.; Kang, D.W.; Ahn, J.S.; Hanover, J.A.
    Versatile O-GlcNAc transferase assay for high-throughput identification of enzyme variants, substrates, and inhibitors (2014), Bioconjug. Chem., 25, 1025-1030.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
analysis single-well OGT enzyme assay that utilizes His6-tagged substrates, a chemoselective chemical reaction, and unpurified OGT. The high-throughput Ni-nitrilotriacetic acid plate OGT assay facilitates discovery of OGT-specific inhibitors on versatile substrates and the characterization of new enzyme variants Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O15294
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nucleoporin p62 + UDP-N-azidoacetylglucosamine
-
Homo sapiens ? + UDP
-
?

Synonyms

Synonyms Comment Organism
ncOGT
-
Homo sapiens
nuclear cytoplasmic OGT
-
Homo sapiens