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Literature summary for 2.4.1.255 extracted from

  • Xu, J.; Wang, S.; Viollet, B.; Zou, M.H.
    Regulation of the proteasome by AMPK in endothelial cells: the role of O-GlcNAc transferase (OGT) (2012), PLoS ONE, 7, e36717.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
UDP-N-acetyl-D-glucosamine
-
Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Synonyms

Synonyms Comment Organism
O-GlcNAc transferase
-
Mus musculus
OGT
-
Mus musculus

General Information

General Information Comment Organism
malfunction siRNA-mediated knockdown of the enzyme enhances 26S proteasome assembly and activity Mus musculus
metabolism enzyme activation of by UDP-GlcNAc blocks compound C-induced increases in 26S proteasome assembly and activation Mus musculus
physiological function the enzyme plays a major role in AMPK regulation of the proteasome Mus musculus