Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli and HEK-293 cells | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O15294 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-GlcNAc + c-MYC intron binding protein 1 | - |
Homo sapiens | UDP + N-acetyl-D-gluosaminyl-[c-MYC intron binding protein 1] | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * about 110000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
O-GlcNAc transferase | - |
Homo sapiens |
O-linked beta-N-acetylglucosamine transferase | - |
Homo sapiens |
OGT | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme knockdown results in nuclear factor-kappaB reporter activation in the cells treated with 10 ng/ml tumor necrosis factor-alpha | Homo sapiens |
physiological function | a post-translational modification enzyme that adds an O-linked beta-N-acetylglucosamine monosaccharide to serine or threonine residues of various proteins | Homo sapiens |