Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-deoxy-D-glucose | 0.4 M, 68% inhibition | Mammalia | |
Ca2+ | above 4 mM | Mammalia | |
D-arabinose | 0.4 M, 13% inhibition | Mammalia | |
D-ribose | 0.4 M, 59% inhibition | Mammalia | |
D-xylose | 0.4 M, 36% inhibition | Mammalia | |
L-arabinose | 0.4 M, 54% inhibition | Mammalia | |
L-sorbose | 0.4 M, 45% inhibition | Mammalia | |
L-Xylose | 0.4 M, 16% inhibition | Mammalia | |
Mg2+ | above 4 mM | Mammalia | |
additional information | alpha-lactalbumin strongly inhibits the transfer of galactose to free N-acetylglucosamine | Mammalia | |
UDPglucose | - |
Mammalia |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Mammalia | |
additional information | - |
additional information | - |
Homo sapiens | |
additional information | - |
additional information | - |
Bos taurus | |
1400 | - |
glucose | reaction in absence of alpha-lactalbumin | Bos taurus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | - |
Homo sapiens | |
Mn2+ | - |
Bos taurus | |
Mn2+ | not replaceable by Mg2+, Ca2+ | Mammalia |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
75000 | - |
gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Capra hircus | - |
- |
- |
Homo sapiens | - |
- |
- |
Mammalia | - |
female | - |
Mus musculus | - |
- |
- |
Ovis aries | - |
- |
- |
Sus scrofa | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | - |
Mammalia |
glycoprotein | - |
Bos taurus |
glycoprotein | the glycoprotein contains 1.1% sialic acid, 5.03% galactosamine, 2.47% glucosamine, 2.36% galactose, 0.87% mannose and 0.87% fucose | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
mammary gland | - |
Mammalia | - |
mammary gland | - |
Mus musculus | - |
mammary gland | - |
Homo sapiens | - |
mammary gland | - |
Bos taurus | - |
milk | - |
Bos taurus | - |
milk | - |
Ovis aries | - |
milk | - |
Capra hircus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dUDPgalactose + D-glucose | - |
Mammalia | lactose + dUDP | - |
? | |
dUDPgalactose + D-glucose | dUDPgalactose is 80% as effective as UDP-D-galactose | Bos taurus | lactose + dUDP | - |
? | |
UDPgalactose + cellobiose | 7.5% of the activity of glucose | Bos taurus | ? | - |
? | |
UDPgalactose + D-glucose | - |
Mammalia | lactose + UDP | - |
? | |
UDPgalactose + D-glucose | - |
Mus musculus | lactose + UDP | - |
? | |
UDPgalactose + D-glucose | - |
Homo sapiens | lactose + UDP | - |
? | |
UDPgalactose + D-glucose | - |
Sus scrofa | lactose + UDP | - |
? | |
UDPgalactose + D-glucose | - |
Ovis aries | lactose + UDP | - |
? | |
UDPgalactose + D-glucose | - |
Capra hircus | lactose + UDP | - |
? | |
UDPgalactose + D-glucose | the galactosyl transferase can catalyze the transfer of galactose to glucose to form lactose in the absence of alpha-lactalbumin provided the glucose concentration is high | Bos taurus | lactose + UDP | - |
? |