Literature summary for 2.4.1.212 extracted from

Nishitsuka, K.; Kashiwagi, Y.; Tojo, N.; Kanno, C.; Takahashi, Y.; Yamamoto, T.; Heldin, P.; Yamashita, H.
Hyaluronan production regulation from porcine hyalocyte cell line by cytokines (2007), Exp. Eye Res., 85, 539-545.

Search for more literature for 2.4.1.212

Activating Compound

Activating Compound	Comment	Organism	Structure
platelet derived growth factor-BB	PDGF-BB	Sus scrofa
transforming growth factor-beta	TGF-beta	Sus scrofa

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Sus scrofa	16020	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
UDP-alpha-D-glucuronate + N-acetyl-beta-D-glucosaminyl-(1-4)-beta-D-glucuronosyl-(1-3)-[nascent hyaluronan]	Sus scrofa	-	UDP + beta-D-glucuronosyl-(1-3)-N-acetyl-beta-D-glucosaminyl-(1-4)-beta-D-glucuronosyl-(1-3)-[nascent hyaluronan]	-	?
UDP-alpha-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1-3)-N-acetyl-beta-D-glucosaminyl-(1-4)-[nascent hyaluronan]	Sus scrofa	-	UDP + N-acetyl-beta-D-glucosaminyl-(1-4)-beta-D-glucuronosyl-(1-3)-N-acetyl-beta-D-glucosaminyl-(1-4)-[nascent hyaluronan]	-	?

Organism

Organism	UniProt	Comment	Textmining
Sus scrofa	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
eye	vitreous body	Sus scrofa	-
PH-5 cell	-	Sus scrofa	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
UDP-alpha-D-glucuronate + N-acetyl-beta-D-glucosaminyl-(1-4)-beta-D-glucuronosyl-(1-3)-[nascent hyaluronan]	-	Sus scrofa	UDP + beta-D-glucuronosyl-(1-3)-N-acetyl-beta-D-glucosaminyl-(1-4)-beta-D-glucuronosyl-(1-3)-[nascent hyaluronan]	-	?
UDP-alpha-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1-3)-N-acetyl-beta-D-glucosaminyl-(1-4)-[nascent hyaluronan]	-	Sus scrofa	UDP + N-acetyl-beta-D-glucosaminyl-(1-4)-beta-D-glucuronosyl-(1-3)-N-acetyl-beta-D-glucosaminyl-(1-4)-[nascent hyaluronan]	-	?

Synonyms

Synonyms	Comment	Organism
Has2	-	Sus scrofa
hyaluronan synthase	-	Sus scrofa

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Release 2023.1 (January 2023)