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Literature summary for 2.4.1.18 extracted from

  • Zhao, J.; Chen, H.; Davidson, T.; Kluz, T.; Zhang, Q.; Costa, M.
    Nickel-induced 1,4-alpha-glucan branching enzyme 1 up-regulation via the hypoxic signaling pathway (2004), Toxicol. Appl. Pharmacol., 196, 404-409.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Co2+ upregulates GBE1 gene transcription Mus musculus
Ni2+ upregulates the GBE1 gene both in vitro and in vivo Homo sapiens
Ni2+ upregulates the GBE1 gene both in vitro and in vivo, in PW cell line, liver, lung, kidney and spleen. Ni2+ mimics hypoxia, GBE1 is upregulated by hypoxia Mus musculus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
-
Homo sapiens
-
HT-29 cell
-
Homo sapiens
-
kidney
-
Mus musculus
-
liver
-
Mus musculus
-
lung
-
Mus musculus
-
spleen
-
Mus musculus
-

Synonyms

Synonyms Comment Organism
1,4-alpha-glucan branching enzyme 1
-
Mus musculus
1,4-alpha-glucan branching enzyme 1
-
Homo sapiens
GBE1
-
Mus musculus
GBE1
-
Homo sapiens