Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.1.17 extracted from

  • Collier, A.C.; Yamauchi, Y.; Sato, B.L.; Rougee, L.R.; Ward, M.A.
    UDP-glucuronosyltransferase 1a enzymes are present and active in the mouse blastocyst (2014), Drug Metab. Dispos., 42, 1921-1925.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.1.17

Cloned(Commentary)

Cloned (Comment) Organism
Ugt1a enzymes expression analysis in blastocysts, overview Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Mus musculus 5737
-
nucleus
-
 Mus musculus 5634
-

Organism

Organism UniProt Comment Textmining
Mus musculus Q64435 UGT1A6; C57BL/6 crossed with DBA/2, gene UGT1A6
-
Mus musculus B6D2F1 Q64435 UGT1A6; C57BL/6 crossed with DBA/2, gene UGT1A6
-

Source Tissue

Source Tissue Comment Organism Textmining
blastocyst obtained after in vitro fertilization with gametes from B6D2F1 hybrid mice and from embryo culture. The blastocysts express Ugt1a globally, in the cytoplasm and nuclei of all of the cells, presence of Ugt1a6 but not Ugt1a1, Ugt1a3, Ugt1a4, or Ugt1a9. The Ugt2b proteins are not detected, Immunofluorescence analysis and Western blot Mus musculus
-

Synonyms

Synonyms Comment Organism
UDP-glucuronosyltransferase 1A
-
 Mus musculus
UGT1A6
-
 Mus musculus

General Information

General Information Comment Organism
physiological function UDP-glucuronosyltransferase (UGT) enzymes are critical for regulating nutrients, hormones, and endobiotics, as well as for detoxifying xenobiotics. Ugt1a proteins are present and active in preimplantation murine embryos and point to a potential role for these proteins in implantation and early embryonic and fetal development. Mus musculus