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Literature summary for 2.4.1.17 extracted from

  • Abildskov, K.; Weldy, P.; Garland, M.
    Molecular cloning of the baboon UDP-glucuronosyltransferase 2B gene family and their activity in conjugating morphine (2010), Drug Metab. Dispos., 38, 545-553.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in HEK-293 cell Papio anubis

Organism

Organism UniProt Comment Textmining
Papio anubis D2SML9 isoform UGT2B43
-
Papio anubis D2SMM0 isoform UGT2B42
-
Papio anubis D2SMM1 isoform UGT2B41
-
Papio anubis D2SMM2 isoform UGT2B39
-
Papio anubis D2SMM3 isoform UGT2B40
-
Papio anubis D2SMM4 isoform UGT2B46
-
Papio anubis D2SMM5 isoform UGT2B45
-
Papio anubis D2SMM6 isoform UGT2B44
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Papio anubis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-D-glucuronate + morphine
-
Papio anubis UDP + morphine 3-O-beta-D-glucuronoside
-
?
UDP-D-glucuronate + morphine
-
Papio anubis UDP + morphine 6-O-beta-D-glucuronoside
-
?

Synonyms

Synonyms Comment Organism
UGT2B39
-
Papio anubis
UGT2B40
-
Papio anubis
UGT2B41
-
Papio anubis
UGT2B42
-
Papio anubis
UGT2B43
-
Papio anubis
UGT2B44
-
Papio anubis
UGT2B45
-
Papio anubis
UGT2B46
-
Papio anubis