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Literature summary for 2.4.1.17 extracted from

  • Al-Zoughool, M.; Talaska, G.
    4-Aminobiphenyl N-glucuronidation by liver microsomes: optimization of the reaction conditions and characterization of the UDP-glucuronosyltransferase isoforms (2006), J. Appl. Toxicol., 26, 524-532.
    View publication on PubMed
Search for more literature for 2.4.1.17

Activating Compound

Activating Compound Comment Organism Structure
alamethicin 0.05 mg//g protein, 8fold increase in activity Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
hecogenin competitive Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0588
-
 4-aminobiphenyl
-
 Homo sapiens
0.2275
-
 4-aminobiphenyl
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum inner membrane Homo sapiens 5783
-
microsome
-
 Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens O60656
-
-
Homo sapiens P22310
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-glucuronate + 4-aminobiphenyl
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
bilirubin-specific UDPGT isozyme 2
-
 Homo sapiens
HUG-BR2
-
 Homo sapiens
UDP-glucuronosyltransferase 1A4
-
 Homo sapiens
UDP-glucuronosyltransferase 1A9
-
 Homo sapiens
UDPGT
-
 Homo sapiens
UGT-1D
-
 Homo sapiens
UGT1-04
-
 Homo sapiens
UGT1-9
-
 Homo sapiens
UGT1.4
-
 Homo sapiens
UGT1.9
-
 Homo sapiens
UGT1A4
-
 Homo sapiens
UGT1A9
-
 Homo sapiens
UGT1D
-
 Homo sapiens