KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.003 | - |
6alpha-hydroxyprogesterone | 37°C, pH 7.4 | Homo sapiens | |
0.0038 | - |
testosterone | 37°C, pH 7.4 | Homo sapiens | |
0.0057 | - |
testosterone | 37°C, pH 7.4 | Homo sapiens | |
0.0069 | - |
11alpha-hydroxyprogesterone | 37°C, pH 7.4 | Homo sapiens | |
0.019 | - |
Mn2+[side2] | 37°C, pH 7.4 | Homo sapiens | |
0.055 | - |
6alpha-hydroxyprogesterone | 37°C, pH 7.4 | Homo sapiens | |
0.073 | - |
16alpha-hydroxyprogesterone | 37°C, pH 7.4 | Homo sapiens | |
0.093 | - |
11alpha-hydroxyprogesterone | 37°C, pH 7.4 | Homo sapiens | |
0.211 | - |
16alpha-hydroxyprogesterone | 37°C, pH 7.4 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
11alpha-hydroxyprogesterone + UDP-glucuronate | Homo sapiens | - |
UDP + 11alpha-hydroxyprogesterone-11-O-D-glucuronate | - |
? | |
16alpha-hydroxyprogesterone + UDP-glucuronate | Homo sapiens | UGT2B15 and UGT2B17 are the major enzyme forms involved in the high-affinity component of 16alpha-hydroxyprogesterone glucuronidation | ? | - |
? | |
16alpha-hydroxyprogesterone + UDP-glucuronate | Homo sapiens | - |
UDP + 16alpha-hydroxyprgesterone-16-O-D-glucuronate | - |
? | |
16alpha-hydroxyprogesterone + UDP-glucuronate | Homo sapiens | UGT2B15 and UGT2B17 are the major enzyme forms involved in the high-affinity component of 16alpha-hydroxyprogesterone glucuronidation | UDP + 16alpha-hydroxyprgesterone-16-O-D-glucuronate | - |
? | |
21-hydroxyprogesterone + UDP-glucuronate | Homo sapiens | - |
UDP + 21-hydroxyprogesterone-21-O-D-glucuronate | - |
? | |
6alpha-hydroxyprogesterone + UDP-glucuronate | Homo sapiens | - |
UDP + 6alpha-hydroxyprogesteron-6-O-alpha-D-glucuronate | - |
? | |
testosterone + UDP-glucuronate | Homo sapiens | UGT2B15 and UGT2B17 are the major enzyme forms involved in human liver microsomal testosterone 17beta-glucuronidation | UDP + testosterone beta-D-glucuronoside | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O60656 | - |
- |
Homo sapiens | O75795 | - |
- |
Homo sapiens | P16662 | - |
- |
Homo sapiens | P22310 | - |
- |
Homo sapiens | P54855 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
11alpha-hydroxyprogesterone + UDP-glucuronate | - |
Homo sapiens | UDP + 11alpha-hydroxyprogesterone-11-O-D-glucuronate | - |
? | |
16alpha-hydroxyprogesterone + UDP-glucuronate | - |
Homo sapiens | ? | - |
? | |
16alpha-hydroxyprogesterone + UDP-glucuronate | UGT2B15 and UGT2B17 are the major enzyme forms involved in the high-affinity component of 16alpha-hydroxyprogesterone glucuronidation | Homo sapiens | ? | - |
? | |
16alpha-hydroxyprogesterone + UDP-glucuronate | - |
Homo sapiens | UDP + 16alpha-hydroxyprgesterone-16-O-D-glucuronate | - |
? | |
16alpha-hydroxyprogesterone + UDP-glucuronate | UGT2B15 and UGT2B17 are the major enzyme forms involved in the high-affinity component of 16alpha-hydroxyprogesterone glucuronidation | Homo sapiens | UDP + 16alpha-hydroxyprgesterone-16-O-D-glucuronate | - |
? | |
21-hydroxyprogesterone + UDP-glucuronate | - |
Homo sapiens | UDP + 21-hydroxyprogesterone-21-O-D-glucuronate | - |
? | |
6alpha-hydroxyprogesterone + UDP-glucuronate | - |
Homo sapiens | UDP + 6alpha-hydroxyprogesteron-6-O-alpha-D-glucuronate | - |
? | |
testosterone + UDP-glucuronate | - |
Homo sapiens | UDP + testosterone beta-D-glucuronoside | - |
? | |
testosterone + UDP-glucuronate | UGT2B15 and UGT2B17 are the major enzyme forms involved in human liver microsomal testosterone 17beta-glucuronidation | Homo sapiens | UDP + testosterone beta-D-glucuronoside | - |
? |
Synonyms | Comment | Organism |
---|---|---|
UGT1A4 | - |
Homo sapiens |
UGT1A9 | - |
Homo sapiens |
UGT2B15 | - |
Homo sapiens |
UGT2B17 | - |
Homo sapiens |
UGT2B7 | - |
Homo sapiens |