Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Flufenamic acid | 0.02-0.5 mM, completely inhibits glucuronidation of 4-methylumbelliferone; 0.02-0.5 mM, inhibits glucuronidation of 4-methylumbelliferone | Homo sapiens | |
Mefenamic acid | 0.02-0.5 mM, completely inhibits glucuronidation of 4-methylumbelliferone; 0.02-0.5 mM, inhibits glucuronidation of 4-methylumbelliferone | Homo sapiens | |
niflumic acid | 0.02-0.5 mM, 66% inhibition of glucuronidation of 4-methylumbelliferone; 0.02-0.5 mM, inhibits glucuronidation of 4-methylumbelliferone | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.048 | - |
Flufenamic acid | - |
Homo sapiens | |
0.135 | - |
niflumic acid | - |
Homo sapiens | |
0.449 | - |
Mefenamic acid | - |
Homo sapiens | |
7.344 | - |
niflumic acid | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O60656 | - |
- |
Homo sapiens | P16662 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | cortex | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-methylumbelliferone + UDP-glucuronate | - |
Homo sapiens | UDP + 4-methylumbelliferyl-7-O-beta-D-glucuronide | - |
? | |
UDP-glucuronate + flufenamic acid | - |
Homo sapiens | ? | - |
? | |
UDP-glucuronate + mefenamic acid | - |
Homo sapiens | ? | - |
? | |
UDP-glucuronate + niflumic acid | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
3,4-catechol estrogen specific UDPGTh-2 | - |
Homo sapiens |
UFT1A9 | - |
Homo sapiens |
UGT2B7 | - |
Homo sapiens |