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Literature summary for 2.4.1.17 extracted from
- Differential effects of phospholipids on two similar forms of UDP-glucuronyltransferase purified from rat liver and kidney microsomes (1991), J. Biochem., 110, 50-53.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| dilauroylphosphatidylcholine | activity towards 4-methylumbelliferone: increased liver enzyme activity | Rattus norvegicus |  |
| lysophosphatidylcholine | activation | Rattus norvegicus | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| dilauroylphosphatidylcholine | activity towards 4-methylumbelliferone: decreased kidney enzyme activity | Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Rattus norvegicus | - |
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-naphthol + UDP-glucuronate | - |
Rattus norvegicus | naphth-1-yl-beta-D-glucuronide + UDP | - |
? | |
| 4-methylumbelliferone + UDP-glucuronate | - |
Rattus norvegicus | UDP + 4-methylumbelliferyl-7-O-beta-D-glucuronide | - |
? | |
| 4-nitrophenol + UDP-glucuronate | - |
Rattus norvegicus | 4-nitrophenyl beta-D-glucuronide + UDP | - |
? | |
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