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Literature summary for 2.4.1.16 extracted from

  • Xu, Y.B.; Li, H.P.; Zhang, J.B.; Song, B.; Chen, F.F.; Duan, X.J.; Xu, H.Q.; Liao, Y.C.
    Disruption of the chitin synthase gene CHS1 from Fusarium asiaticum results in an altered structure of cell walls and reduced virulence (2010), Fungal Genet. Biol., 47, 205-215.
    View publication on PubMed

Application

Application Comment Organism
agriculture specific disruption of the CHS1 gene results in a 58% reduction of chitin synthase activity, accompanied by decreases of 35% in chitin content, 22% in conidiation, and 16% in macroconidium length. The mutant displays significantly reduced pathogenicity on wheat spikes and seedlings Fusarium asiaticum

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Fusarium asiaticum
-
isoform CHS1
-

General Information

General Information Comment Organism
physiological function specific disruption of the CHS1 gene results in a 58% reduction of chitin synthase activity, accompanied by decreases of 35% in chitin content, 22% in conidiation, and 16% in macroconidium length. The mutant strain has a growth rate comparable to that of the wild-type on PDA medium but has a 35% increase in the number of nuclear cellulae and exhibits a remarkably increased sensitivity to osmosis stresses. Mutant shows substantial changes in cell wall structures of the macroconidium, ascospore, and mycelium, with the most profound changes in the mycelium. The mutant displays significantly reduced pathogenicity on wheat spikes and seedlings Fusarium asiaticum