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Literature summary for 2.4.1.155 extracted from
- N-Acetylglucosaminyltransferase V negatively regulates integrin alpha5beta1-mediated monocyte adhesion and transmigration through vascular endothelium (2012), Int. J. Oncol., 41, 589-598.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | the enzyme is a potential therapeutic target for vascular inflammatory conditions | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| monocyte | - |
Homo sapiens | - |
| THP-1 cell | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GnT-V | - |
Homo sapiens |
| N-acetylglucosaminyltransferase V | - |
Homo sapiens |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | during interferon-gamma-induced inflammation, the level of GnT-V in THP-1 monocytes are significantly decreased | down |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | decreased enzyme activity due to inflammatory cytokine induction in human monocytes results in enhancement of integrin alpha5beta1-dependent monocyte-vascular endothelium adhesion and transmigration | Homo sapiens |
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Release 2023.1 (January 2023)
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