Application | Comment | Organism |
---|---|---|
medicine | enzyme may be used as diagnostic marker of human cancer or as target molecule for the development of a new therapy | Mus musculus |
Cloned (Comment) | Organism |
---|---|
cDNA from placenta encoding beta3GnT7 is cloned and partially characterized, open reading frame encodes a 397-amino acids protein | Mus musculus |
human ortholog to mouse enzyme beta3GnT7 has the chromosomal locus 2q37.1 | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
45000 | - |
x * 45000, calculated from the amino acid sequence | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | beta3GnT7 may play a role in preventing cells from migrating out of the original tissues and invading surrounding tissues | ? | - |
? | |
additional information | Mus musculus beta3GnT7 | beta3GnT7 may play a role in preventing cells from migrating out of the original tissues and invading surrounding tissues | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q8NFL0 | - |
- |
Mus musculus | Q8K0J2 | beta3GnT7 | - |
Mus musculus beta3GnT7 | Q8K0J2 | beta3GnT7 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cerebellum | very weak expression of beta3GnT7 | Mus musculus | - |
cerebrum | very weak expression of beta3GnT7 | Mus musculus | - |
colon | beta3GnT7 is most strongly expressed in the placenta and colon | Mus musculus | - |
FM3A cell | breast cancer cell line, higher expression of beta3GnT7 in cancer cell lines with low degrees of invasiveness | Mus musculus | - |
heart | very weak expression of beta3GnT7 | Mus musculus | - |
kidney | moderate expression of beta3GnT7 | Mus musculus | - |
KLN205 cell | KLN205-MUC1, lung cancer cell line, higher expression of beta3GnT7 in cancer cell lines with low degrees of invasiveness | Mus musculus | - |
lung | moderate expression of beta3GnT7 | Mus musculus | - |
placenta | beta3GnT7 is most strongly expressed in the placenta at the later stages of gestation and in colon | Mus musculus | - |
small intestine | moderate expression of beta3GnT7 | Mus musculus | - |
stomach | moderate expression of beta3GnT7 | Mus musculus | - |
testis | very weak expression of beta3GnT7 | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | beta3GnT7 may play a role in preventing cells from migrating out of the original tissues and invading surrounding tissues | Mus musculus | ? | - |
? | |
additional information | beta3GnT7 may play a role in preventing cells from migrating out of the original tissues and invading surrounding tissues | Mus musculus beta3GnT7 | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 45000, calculated from the amino acid sequence | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
beta3GnT7 | - |
Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
pI: 8.7 | Mus musculus |