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Literature summary for 2.4.1.143 extracted from

  • Fritz, T.A.; Gabb, M.M.; Wei, G.; Esko, J.D.
    Two N-acetylglucosaminyltransferases catalyze the biosynthesis of heparan sulfate (1994), J. Biol. Chem., 269, 28809-28814.
    View publication on PubMed
Search for more literature for 2.4.1.143

Activating Compound

Activating Compound Comment Organism Structure
CHAPS
-
 Oncorhynchus mykiss
Triton X-100
-
 Oncorhynchus mykiss
Zwittergent 3-12
-
 Oncorhynchus mykiss

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.23
-
 UDP-N-acetylglucosamine pH 6.5, 37°C Oncorhynchus mykiss

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+
-
 Oncorhynchus mykiss
additional information Ca2+, Co2+, Cu2+ and Mg2+ cannot replace Mn2+ Oncorhynchus mykiss

Organism

Organism UniProt Comment Textmining
Oncorhynchus mykiss
-
 CHO-cells
-

Source Tissue

Source Tissue Comment Organism Textmining
ovary
-
 Oncorhynchus mykiss
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-1,4-N-acetylglucosaminyl-R
-
 Oncorhynchus mykiss UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-1,4-N-acetylglucosaminyl-R
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5 8
-
 Oncorhynchus mykiss