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Literature summary for 2.4.1.135 extracted from

  • Mikami, Y.; Fukushima, A.; Kuwada-Kusunose, T.; Sakurai, T.; Kitano, T.; Komiyama, Y.; Iwase, T.; Komiyama, K.
    Whole transcriptome analysis using next-generation sequencing of sterile-cultured Eisenia andrei for immune system research (2015), PLoS ONE, 10, e0118587.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.1.135

Cloned(Commentary)

Cloned (Comment) Organism
gene B3GAT3, a unigene, DNA and amino acid sequence determination and analysis, sequence comparison with the human enzyme and phylogenetic analysis Eisenia andrei

Organism

Organism UniProt Comment Textmining
Eisenia andrei
-
 gene B3GAT3
-

Source Tissue

Source Tissue Comment Organism Textmining
natural killer cell
-
 Eisenia andrei
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the uridine diphosphate binding region plays an important role in enzyme activity of the enzyme Eisenia andrei ?
-
 ?
UDP-glucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein
-
 Eisenia andrei UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein
-
 ?

Subunits

Subunits Comment Organism
More determination of enzyme tertiary structure by homology modelling using the human enzyme structure, PDB ID 1v83 Eisenia andrei

Synonyms

Synonyms Comment Organism
beta-1,3-glucuronyltransferase 1
-
 Eisenia andrei
GlcAT-P
-
 Eisenia andrei

General Information

General Information Comment Organism
additional information gene B3GAT3 is a unigene, pathway enrichment analysis of assembled unigenes, overview. Identification of markers of NK cells. Enzyme structure modelling using the structure of human GlcAT-P as a template Eisenia andrei
physiological function the enzyme mediates a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1, human natural killer-1, also known as CD57, a marker of NK cells Eisenia andrei