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Literature summary for 2.4.1.135 extracted from

  • Helting, T.; Roden, L.
    Biosynthesis of chondroitin sulfate. II. Glucuronosyl transfer in the formation of the carbohydrate-protein linkage region (1969), J. Biol. Chem., 244, 2799-2805.
    View publication on PubMed
Search for more literature for 2.4.1.135

Inhibitors

Inhibitors Comment Organism Structure
3-O-beta-D-Galactosyl-galactose with 3-galactosyl-4-galactosyl-xylose as substrate Gallus gallus
additional information no inhibition by chondroitin 6-sulfate trisaccharides or pentasaccharides containing N-acetylglucosamine 6-sulfate at their non-reducing termini Gallus gallus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane bound Gallus gallus 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ required Gallus gallus
Mn2+ 15 mM Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDPglucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein Gallus gallus involved in the biosynthesis of the polysaccharide-protein-linkage region of proteochondroitin sulfate ?
-
 ?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cartilage
-
 Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information galactosyl-beta-1,6-galactose is a less effective acceptor substrate Gallus gallus ?
-
 ?
additional information galactosyl-beta-1,4-galactose is a less effective acceptor substrate Gallus gallus ?
-
 ?
UDPglucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein involved in the biosynthesis of the polysaccharide-protein-linkage region of proteochondroitin sulfate Gallus gallus ?
-
 ?
UDPglucuronate + 3-beta-D-galactosyl-D-galactose transfer to non-reducing terminal Gallus gallus UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-D-galactose
-
 ?
UDPglucuronate + 3-beta-D-galactosyl-D-galactosyl-4-xylose
-
 Gallus gallus UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-D-galactosyl-4-xylose
-
 ?
UDPglucuronate + 3-beta-D-galactosyl-D-galactosyl-4-xylosylserine
-
 Gallus gallus UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-D-galactosyl-4-xylosylserine
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5 7.5
-
 Gallus gallus