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Literature summary for 2.4.1.12 extracted from

  • Fugelstad, J.; Bouzenzana, J.; Djerbi, S.; Guerriero, G.; Ezcurra, I.; Teeri, T.; Arvestad, L.; Bulone, V.
    Identification of the cellulose synthase genes from the oomycete Saprolegnia monoica and effect of cellulose synthesis inhibitors on gene expression and enzyme activity (2009), Fungal Genet. Biol., 46, 759-767.
    View publication on PubMed
Search for more literature for 2.4.1.12

Cloned(Commentary)

Cloned (Comment) Organism
gene cesA2, DNA and amino acid sequence determination and analysis, sequence comparison and phylogenetic analysis Saprolegnia monoica
gene cesA4, DNA and amino acid sequence determination and analysis, sequence comparison and phylogenetic analysis Saprolegnia monoica

Inhibitors

Inhibitors Comment Organism Structure
2,6-dichlorobenzonitrile affects mycelial growth; affects mycelial growth Saprolegnia monoica
Congo red affects mycelial growth; affects mycelial growth Saprolegnia monoica

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Saprolegnia monoica 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Saprolegnia monoica

Organism

Organism UniProt Comment Textmining
Saprolegnia monoica C9WPJ9 CesA2; Pringsheim 539-67 Dick, three CesA homologues
-
Saprolegnia monoica C9WPK1 Pringsheim 539-67 Dick, CesA4; three CesA homologues
-

Source Tissue

Source Tissue Comment Organism Textmining
mycelium
-
 Saprolegnia monoica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information UDP-glucose acts as glycosyl donor in glucan synthesis, product analysis Saprolegnia monoica ?
-
 ?

Subunits

Subunits Comment Organism
More CesA isozymes all contains the D,D,D,QXXRW signature, their N-terminal ends exhibited oomycete-specific domains, i.e. Pleckstrin homology domains, or conserved domains of an unknown function together with additional putative transmembrane domains Saprolegnia monoica

Synonyms

Synonyms Comment Organism
CesA2
-
 Saprolegnia monoica
CESA4
-
 Saprolegnia monoica
More oomycete CesAs form a clade of their own Saprolegnia monoica

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6
-
 assay at Saprolegnia monoica

Expression

Organism Comment Expression
Saprolegnia monoica CesA inhibition by 2,6-dichlorobenzonitrile or Congo Red results in increased expression of all CesA genes, overview up

General Information

General Information Comment Organism
physiological function all CesA isozymes are directly involved in cellulose biosynthesis Saprolegnia monoica